This study compares the effectiveness and safety of leukocyte-poor platelet-rich plasma (LP-PRP) versus leukocyte-rich platelet-rich plasma (LR-PRP) in treating chronic cervical facetogenic pain, focusing on pain relief and functional improvement over 3 and 6 months.
Both LP-PRP and LR-PRP significantly reduced pain and improved neck function, but LR-PRP showed superior long-term benefits at 6 months, with greater reductions in pain intensity and disability scores. More participants receiving LR-PRP achieved clinically meaningful improvements, and LR-PRP was associated with fewer adverse events compared to LP-PRP, which had more cases of increased pain and muscle spasms.
PRP is an emerging treatment for chronic cervical facetogenic pain, but the role of leukocyte concentration in PRP preparations remains unclear. This pooled analysis suggests that LR-PRP, with its higher leukocyte content, may provide enhanced and safer therapeutic outcomes compared to LP-PRP. These findings support further research to optimize PRP formulations for better management of chronic neck pain.
If you have questions or comments about this post, please email us at research@vivocura.ca
NOTE: This was written to help the reader become familiar with some of the research we are doing here at Vivo Cura Health. This post, and all other content on this website are not intended to be a substitute for medical advice, diagnosis, or treatment. Please consult with a certified healthcare provider to discuss if a treatment is right for you.